Oral Semaglutide

the active ingredient in Rybelsus®.

The oral form of semaglutide, for patients who prefer or are better suited to a daily pill over injections.

How it works

Same GLP-1 receptor agonist mechanism as injectable semaglutide, formulated for oral absorption.

Who it's typically considered for

Patients evaluated as candidates for GLP-1 therapy who prefer not to self-inject.

Common side effects

• — Nausea
• — Diarrhea or constipation
• — Decreased appetite
• — Fatigue

Who should not take this

• — Pregnancy or breastfeeding
• — Personal or family history of medullary thyroid carcinoma or MEN2
• — Severe gastrointestinal disease